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Ma Fuqiang
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mafuqiang318@ sibet.ac.cn
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No.88,Keling Road, Suzhou New District, China


Dr Fuqiang Ma is a professor at the Medical Enzyme Engineering Center of the Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences. Mainly engaged in medical enzyme engineering, enzyme molecular transformation and ultra-high-throughput screening, enzymatic DNA synthesis and other aspects of research. In 2016, he graduated from Shanghai Jiao Tong University and went to the University of Michigan for an exchange visit from 2014 to 2015. He has published more than ten papers in the international top journals such as Nature Communications, Science Advances, and Analytical Chemistry in the field of enzymology as a communication author or first author.


1. Single-cell microreactor-based enzyme/strain ultra-high throughput screening platform

2. Novel DNA polymerase mining, molecular engineering, and application

3. Research and development of enzymes and reagents for molecular diagnosis / high throughput sequencing

4. High-efficiency molecular engineering of transaminase and its applications in chiral amine synthesis

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1、Xue Bai+,Daixi Li*+,Fuqiang Ma+,Xi Deng,Manjie Luo,Yan Feng,Guangyu Yang*.Improved thermostability of creatinase from Alcaligenes Faecalis through non-biased phylogenetic consensus-guided mutagenesis,Microbial Cell Factories, IF:3.752, DOI:10.1186/s12934-020-01451-9,公开发表日期:2020-10-14

2、Fuqiang Ma*,Tianjie Guo,Yifan Zhang,Xue Bai,Changlong Li,Xi Deng, Daixi Li,Katsuo Kurabayashi, Guang-yu Yang. An ultrahigh-throughput screening platform based on flow cytometric droplet sorting for mining novel enzymes from metagenomic libraries,Environmental Microbiology,IF:5.434,DOI:10.1111/1462-2920.15257,公开发表时间:2020-09-28

3、Fuqiang Ma, Meng Ting Chung, Yuan Yao, Robert Nidetz, Lap Man Lee, Allen P. Liu, Yan Feng, Katsuo Kurabayashi, Guang-yu Yang. Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform. Nature Communications 2018, 9:1030. (IF: 11.878).

4、Yumeng Tan, Yong Zhang, Yunbin Han, Hao Liu, Haifeng Chen, Fuqiang Ma, Stephen G Withers, Yan Feng, Guangyu Yang. Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method Science Advances已接收,(IF:12.804)

5、Fuqiang Ma, Yuan Xie, Junyao Hao, Bo Zhao, Yan Feng, Guang-Yu Yang et al. Efficient molecular engineering to generate thermostable enzymes for robust diagnosis of glycated hemoglobin A1c. in submission to 德国应化. (IF: 8.173).

6、Fuqiang Ma, Yuan Xie, Manjie Luo, Shuhao Wang, You Hu, Yukun Liu, Yan Feng, and Guang-Yu Yang. Sequence homolog-based molecular engineering for shifting the enzymatic pH optimum. Synthetic and Systems Biotechnology 2016, 1: 195-206.

7、Fuqiang Ma, Michael Fischer, Yunbin Han, Stephen G. Withers, Yan Feng, and Guang-Yu Yang. Substrate Engineering Enabling Fluorescence Droplet Entrapment for IVC-FACS-Based Ultrahigh-Throughput Screening. Analytical Chemistry, 2016, 88(17):8587-8595. (IF: 6.35)

8、Publication Date (Web): August 5, 2016 (Article) DOI: 10.1021/acs.analchem.6b01712

9、Fuqiang Ma, Yuan Xie, Chen Huang, Yan Feng, Guang-Yu Yang. An improved single cell ultrahigh throughput screening method based on in vitro compartmentalization. Plos One, 2014, 9(2):e89785. (IF: 2.776) 发表时间:2014.2.24


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