Xin Gao, Ph.D. is engaged in teaching and scientific research in Capital Medical University, Japan Gifu University, the Institute of Methodist Hospital at Texas Medical Center, Radiology Department of Iowa University Hospital

Xin Gao is engaged mainly in researches on interventional diagnosis and therapy. In the background of interventional radiology and to meet actual clinic need, the researches are focused on the breakthrough of key technologies, including front end multimode imaging technology, preoperative planning & intra-operative navigation technology, and prognostic assessment technique based on clinic big data and artificial intelligence so as to create integrated solution for interventional diagnosis and therapy.

In recent five years, Xin Gao presided over the following scientific research projects: 3 NSFC projects, 1 CAS scientific research equipment development project, 1 CAS international cooperation project, 1 sub project of national major research equipment development project, 4 provincial level projects and 2 city level projects， published over 70 scientific papers, among which 20 papers are included in SCI as the first / correspondence author, and obtained 6 invention patents, 1 utility model patent and 2 software copyrights.

Council member of the Medical Instrument Branch of China Instrument and Control Society, member of the Youth Committee of Chinese Society of Biomedical Engineering, and member of editorial board of Journal of Graphics

(1) Precision medicine based on omics big data: conducting data feature extraction and analysis on correlation between different omics, predicting individual disease risk and assessing prognosis and therapy effect so as to provide solution for clinic decision. These research works are based on analysis of imaging omics data, genomicis data, clinic laboratory test data and pathologic data with artificial intelligence and data analysis and mining technique.

(2) Operative planning and navigation: quantitative route planning and risk assessment based on multi-modality image information, lesion location information and patient imaging anatomical information; precision positioning and targeted therapy of lesion through various positioning techniques such as optical, electromagnetic and intra-operative angiography.

(3) Low dose cone-beam CT imaging: development of new type low dose CT-like devices and cone-beam CT imaging system based on flat panel detector, and research on precision 3-D reconstruction of low sampling rate projection data, 3-D reconstruction of local projection area and multi-energy/spectral CT information separation.

§   Sponsored by the 100 Talents Program of the Chinese Academy of Sciences (2012)

§   Sponsored by the High-level Talents of Innovation and Entrepreneurship Program of Jiangsu Province (2013)

§   Third-level talented scientist of the “333 High-level Talent Training Program” of Jiangsu Province (2013)

§   “High-level Tight Talent for Colleges and Research Institutes” of Suzhou (2011)

§   Excellent Talent of Beijing (2006)

Selected Papers in Journals

Xiaoli Zhu^？, Zhao Ran^？, Kangshun Zhu, Wensou Huang, Xin Gao*, “Method for Calculating the Bending Angle of Puncture Needle in Preoperative Planning for Transjugular Intrahepatic Portal Systemic Shunt (TIPS)”, Computational and Mathematical Methods in Medicine, Apr. 11, 2018. (SCI)

Junming Jian, Wei Xia, Rui Zhang, Jinhui Gu, Xiaodong Wu, Xiaochun Meng*, Xin Gao*, "Fully convolutional networks (fcns)-based segmentation method for colorectal tumors on t2-weighted magnetic resonance images", Australasian Physical & Engineering Sciences in Medicine, Apr. 4, 2018. (SCI)

Xuejun Zhang, Xiaomin Tan, Xin Gao*, Dongbo Wu, Xiangrong Zhou, Hiroshi Fujita, "Non-rigid registration of multi-phase liver CT data using fully automated landmark detection and TPS deformation", Cluster Computing-The Journal of Networks, Software Tools and Applications, 26 March, 2018. (SCI)

Wei Xia^？, Ying Chen^？, Rui Zhang, Zhuangzhi Yan, Xiaobo Zhou, Bo Zhang, Xin Gao*, “Radiogenomics of Hepatocellular Carcinoma: Multiregion Analysis-Based Identification of Prognostic Imaging Biomarkers by Integrating Gene Data——A Preliminary Study”, Physics in Medicine and Biology, 63, 035044, 2018. (SCI)

Rui Zhang, Lin Huang, Wei Xia, Bo Zhang, Bensheng Qiu, Xin Gao*, “Multiple supervised residual network for osteosarcoma segmentation in CT images”, Computerized Medical Imaging and Graphics, Vol. 63, pp. 1-8, 2018. (SCI)

Wei Xia, Zhuangzhi Yan*, Xin Gao*, “Volume Fractions of DCE-MRI Parameter as Early Predictor of Histologic Response in Soft Tissue Sarcoma: A Feasibility Study”, European Journal of Radiology, 95: 228-235, 2017. (SCI).

Yangchuan Liu, Yuguo Tang*, Xin Gao^*, “GATE Monte Carlo Simulation of Dose Distribution Using MapReduce in a Cloud Computing Environment”, Australasian Physical & Engineering Sciences in Medicine, 40:777–783, 2017. (SCI)

Lin Huang, Wei Xia, Bo Zhang, Bensheng Qiu, Xin Gao*, "MSFCN-Multiple Supervised Fully Convolution Network for the Osteosarcoma Segmentation of CT Images", Computer Methods and Programs in Biomedicine, Vol. 143, pp. 67-74, 2017. (SCI)

Xuan Zhou^？, Xin Gao^？, Jiajun Wang*, et al., "Eye tracking data guided feature selection for image classification", Pattern Recognition, Vol.63, pp. 56-70, 2017. (SCI)

Hui Zhang, Si Chen, Wei Zou, Danfeng Hu, Xin Gao*, and Jiajun Wang*, “Bayesian reconstruction of quantitative photoacoustic tomography considering modeling error of the optical diffusion equation”, Optical Engineering, Vol. 55, No. 9, 2016. (SCI)

Xuejun Zhang*, Xin Gao*, Brent J. Liu, Kevin Ma, Wen Yan, Long Liling, Huang Yuhong, Hiroshi Fujita, "Effective staging of fibrosis by the selected texture features of liver: Which one is better, CT or MR imaging?", Computerized Medical Imaging and Graphics, Vol. 47, pp. 227-236, 2015. (SCI)

Jingya Zhang, Jiajun Wang*, Xiuying Wang, Xin Gao*, Dagan Feng, “Physical Constraint Finite Element Model for Medical Image Registration”, PLoS One, Oct. 23, 2015. (SCI)

Zhu-Hong You, Jianqiang Li*, Xin Gao*, Zhou He, Lin Zhu, Ying-Ke Lei, and Zhiwei Ji, “Detecting Protein-Protein Interactions with a Novel Matrix-Based Protein Sequence Representation and Support Vector Machines”, BioMed Research International, Vol. 2, pp. 1-9, 2015. (SCI)

YuAn Huang, Zhuhong You*, Xin Gao, Leon Wong, Lirong Wang*, "Using Weighted Sparse Representation Model Combined with Discrete Cosine Transformation to Predict Protein-Protein Interactions from Protein Sequence", BioMed Research International, 2015. (SCI)

Mingjian Su, Xuejun Zhang, Ximin Wang, Brent J Liu, Xin Gao, Zuojun Zhang, and Bin Zhou, "Vessel extraction on ocular fundus images by using Gabor filter bank", Computer Aided Drafting, Design and Manufacturing, Vol. 25, No. 1, pp. 28-36, 2015.

Xuejun Zhang, Bin Zhou, Xianghe Qu, Xiaomin Tan, Xin Gao, Wen Yan, Long Liling, and Hiroshi Fujita, "Selection of optimal shape features for staging Hepatic fibrosis on CT image", Journal of Medical Imaging and Health Informatics, Vol. 5, No. 8, pp. 1926-1930, 2015. (SCI)

ZhuHong You, Shuai Li*, Xin Gao*, Xin Luo and Zhen Ji, "Large-Scale Protein-Protein Interactions Detection by Integrating Big Biosensing Data with Computational Model", BioMed Research International, Vol. 2014, pp. 1-9, 2014. (SCI)

Xueli Cui, Xin Gao*, Wei Xia, Yangchuan Liu and Zhiyuan Liang*, "Patient specific respiratory motion modeling using a limited number of 3D lung CT images", Bio-Medical Materials and Engineering, Vol.24, No.6, pp: 3113-3120, 2014. (SCI)

Wei Xia, Xin Gao*, “A Fast Deformable Registration Method for 4D Lung CT in Hybrid Framework”, International Journal of Computer Assisted Radiology and Surgery. Vol. 9, No.4, pp 523-533, 2014. (SCI)

Wei Xia, Xin Gao*, Xiaocong Wang^*, “PSI: Point-Set-and-Intensity-based algorithm for 3D CT deformable registration”, Journal of Medical Imaging and Health Informatics, Vol. 4, No. 3, pp. 444-447, 2014. (SCI)

Lei Wang, Xin Gao*, Zhiyong Zhou, Xiaocong Wang^*, “Evaluation of four similarity measures for 2D/3D registration in image-guided intervention”, Journal of Medical Imaging and Health Informatics, Vol. 4, No. 3, pp. 416-421, 2014. (SCI)

Leo Ai*, Xin Gao, Jinhu Xiong, “Application of mean-shift clustering to Blood oxygen level dependent functional MRI activation detection”, BMC Medical Imaging, Vol. 14, No. 6, 2014. (SCI)

Yangchuan Liu, Xin Gao*, Weiwei Fu, Chuan Xu, Yun Teng, "A Twice Calibrating Method for Binocular Stereovision System", Applied Mechanics and Materials, Vols. 333-335, pp: 161-166, 2013. (EI)

Yangchuan Liu, Xin Gao*, Chuan Xu, Weiwei Fu, Yun Teng, Hongcheng Yang, Tao Zhang, “A sub-pixel extraction method for the center of the circular structure from spot array calibration target”, Applied Mechanics and Materials, Vol. 236-237, pp: 1090-1094, 2012. (EI)

Xin Gao, Zhong Xue, Stephen M. Gottschalk, Catherine M. Bollard, Daniel Lee, Jiong Xing, Stephen C. Wong, “Computer-Assisted Quantitative Evaluation of Therapeutic Responses for Lymphoma Using Serial Imaging”, Academic Radiology, Volume 17, Issue 4, Pages 479-488, 2010. (SCI, EI)

Xin Gao, Youshikazu Uchiyama, Xiangrong Zhou, Takeshi Hara, Hiroshi Fujita, “A Fast and Fully Automatic Method for Cerebrovascular Segmentation on Time-of-Flight (TOF) MRA Image”, Journal of Digital Imaging, Vol 24, No. 4, pp: 609-625, 2011. (SCI, EI)

Hiroshi Fujita, Yoshikazu Uchiyama,Toshiaki Nakagawa, Daisuke Fukuoka, Yuji Hatanaka, Takeshi Hara, Gobert N. Lee, Yoshinori Hayashi, Yuji Ikedo, Xin Gao and Xiangrong Zhou, “Computer-aided diagnosis: The emerging of three CAD systems induced by Japanese health care needs”, Computer Methods and Programs in Biomedicine, Review, Vol. 92, No. 3, pp: 238-248, 2008. (SCI)

Xin Gao, Yuanmei Wang, Cishen Zhang, “Fuzzy vector objective optimization approach to image reconstruction from incomplete projections”, International Journal of Image and Graphics, Vol. 7, No. 1, pp: 1-15, 2007.

Hongxia Yin, Bo Liu, Xin Gao, Xiulai Gao, and Shuqian Luo, "Application of Synchrotron source based DEI method in guinea pig cochleae imaging", Progress in Natural Science, Vol. 17, No. 1, pp: 59-67, 2007. (SCI, EI)

Xin Gao, Shuqian Luo, Hongxia Yin, Maolin Xu, et al. “A micro-tomography method based on X-ray diffraction enhanced imaging for visualizing biological micro-organisms and soft tissue materials”, Computerized Medical Imaging and Graphics, Vol. 30, pp. 339–347, 2006. (SCI, EI)

Hang Shu, Peiping Zhu, Junyu Wang, Xin Gao et al. “Diffraction enhanced imaging computer tomography”, ACTA PHYSICA SINICA, Vol. 55, No. 3, pp: 1099-1106, 2006. (SCI, EI)

Selected Papers Presented at Conferences

Wei Xia, Ying Chen, Bo Zhang, Xin Gao*, “Identification of Prognostic Imaging Biomarkers for Hepatocellular Carcinoma Based on Radiogenomics and Multiregion Analysis”, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2018), July 17-21, 2018, Honolulu, HI, USA. (EI)

Junming Jian, Wei Xia, Rui Zhang, Jinhui Gu, Xiaodong Wu, Xiaochun Meng, Xin Gao*, "Fully Convolutional Networks (FCNs)-Based Segmentation Method for Colorectal Tumors on T2-Weighted Magnetic Resonance Images", IEEE International Symposium on Biomedical Imaging (ISBI'18), Washington, D.C. USA, April 4-7, 2018. (EI)

Yangchuan Liu, Yuguo Tang, Xin Gao*, "An Exponent-based Anisotropic Variational PDE Regularized Image Reconstruction Method for Digital Tomosynthesis", 2016 9th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI 2016), pp: 1364-1368, Datong, China,  October 15-17, 2016. (EI)

Jiaxi He, Cishen Zhang, Ifat-Al Baqee, and Xin Gao*, "A regularized optimization approach to fast image dehazing”, 2015 IEEE International Conference on Signal Processing, Communications and Computing, p: 740-744, Ningbo, China, September 19-22, 2015. (EI)

Wei Xia, Lin Chen, Yu Kuang, Xin Gao*, “DCE-MRI-based imaging biomarkers for the Early Response Evaluation of Chemo-radiation Therapy in Soft Tissue Sarcoma”, 2015 World Molecular Imaging Congress, Honolulu, Hawaii, September 2-5, 2015.

Wei Xia, Xin Gao*, “The standardization of super resolution optical microscopic images based on DICOM”, SPIE Medical Imaging, Orlando, Florida, USA, February 21-26, 2015. (EI)

Xueli Cui, Yangchuan Liu, Wei Xia, Xin Gao*, “Patient Specific Respiratory Motion Modeling by Labeling in Vitro”, Computer Assisted Radiology and Surgery 2014 (CARS 2014), Vol. 9, pp: 32, Fukuoka, Japan, June 25-28, 2014.

Wei Xia, Xin Gao*, Lei Wang, Zhi-yong Zhou, Ran Zhang, “3D Deformable Registration of CT Lung Images Based on Point Set and Intensity Information”, 2013 Annual Meeting of Radiological Society of North America (RSNA 2013), Chicago, USA, December, 1-6, 2013.

Lei Wang, Xin Gao*, “A Comparison of Two Novel Similarity Measures Based On Mutual Information In 2D/3D Image Registration”, Proceedings of 2013 IEEE International Conference on Medical Imaging Physics and Engineering (ICMIPE), pp: 215-218, Shenyang, China, October 19-20, 2013. (EI)

Ran Zhang, Xin Gao*, Lei Wang, Wei Xia, “Evaluation Of Similarity Measures And Optimization Methods For 2D/3D Rigid Registration In Image Guided Interventions”, 13th International Conference on Computer Sciences and Application, Wuhan, China, December 14-15, 2013. (EI)

Leo Ai, Xin Gao, Jinhu Xiong, “Detection of BOLD Functional MRI and Magnetic Source MRI Activations Using Repeated Median Nerve Stimulation”, 19th Annual Meeting of the Organization for Human Brain Mapping, Seattle, Washington, USA. June 16-20, 2013.

Leo Ai, Xin Gao, Jinhu Xiong, “Application of Mean-Shift Clustering in fMRI Analysis”, 19th Annual Meeting of the Organization for Human Brain Mapping, Seattle, Washington, USA, June 16-20, 2013.

Leo Ai, Xin Gao, Jinhu Xiong, “Detection of Hemodynamic Response with Function MRI using Repeated Median Nerve Stimulation”, 26th International Symposium on Cerebral Blood Flow, Metabolic, and Function, pp: 368-369, Shanghai, China, May 20-23, 2013.

Lei Wang, Xin Gao*, Qiang Fang, "A Novel Mutual Information-based Similarity Measure for 2D/3D Registration in Image Guided Intervention", 2013 IEEE International Conference on Orange Technologies, Tainan, Taiwan, March 12-16, 2013. (EI)

Hongcheng Yang, Xin Gao*, Chuan Xu, et al. "Backprojection Weight-based FDK Reconstruction Algorithm for Cone Beam DSA", 5th International Congress on Image and Signal Processing, (BMEI 2012), Chongqing, China, October 16-18, 2012. (EI)

Yangchuan Liu, Xin Gao^*, Chuan Xu, et al. "A Sub-pixel Extraction Method for the Center of the Circular Structure from Spot Array Calibration Target", 3rd International Conference on Information Technology for Manufacturing Systems (ITMS 2012), Qingdao, China, September 8-9, 2012. (EI)

Dezhi Gao, Xin Gao*, Caifang Ni, Tao Zhang*, "MGRG-Morphological Gradient Based 3D Region Growing Algorithm for Airway Tree Segmentation in Image Guided Intervention Therapy", 2nd International Symposium on Bioelectronics and Bioinformatics (ISBB 2011), Suzhou, China, November 3-5, 2011. (EI)

Xin Gao, Tao Zhang, Jinhu Xiong, "Comparison between Spatial and Temporal Independent Component Analysis for Blind Source Separation in fMRI Data", 4th International Conference on BioMedical Engineering and Informatics (BMEI 2011), Shanghai, China, October 15-17, 2011. (EI)

Xin Gao, Leo Ai, Jinhu Xiong, “Detecting neural activity using msMRI and ICA without prior timing information”, 16th Annual Meeting of the Organization for Human Brain Mapping(OHBM 2010), Barcelona, Spain, June 6-10, 2010.

Xiangjun Zhu, Zhong Xue, Xin Gao, Yisheng Zhu, Stephen Wong, “VOLES: Vascularity-oriented level set algorithm for pulmonary vessel segmentation in image guided intervention therapy”, Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI’09), Boston, USA, June 28-July 1, 2009. (EI)

Yoshikazu Uchiyama, Xin Gao, Takeshi Hara, Hiroshi Fujita, et al. "Computerized Detection of Unruptured Aneurysms in MRA Images: Reduction of False Positives Using Anatomical Location Features", Proceedings of SPIE Medical Imaging, Vol. 6915, San Diego, USA, February 17-21. 2008.  (EI)

Hiroshi Fujita, Youshikazu Uchiyama, Toshiaki Nakagawa, Daisuke Fukuoka, Yuji Hatanaka, Takeshi Hara, Yoshinori Hayashi, Yuji Ikedo, Gobert N. Lee, Xin Gao and Xiangrong Zhou “CAD on brain, fundus, and breast images”, Medical Imaging and Informatics, Lecture Notes in Computer Science, Vol. 4987, 358-366, Beijing, China, August 14-16, 2007. (EI)

Xin Gao, Yoshikazu Uchiyama, Xiangrong Zhou, Takeshi Hara, Hiroshi Fujita, "An Improved Powell Method for Registration of MRI and MRA", Proceedings of Institute of Electornics, Information and Communication Engineers (IEICE) on Medical Imaging, pp: 181-186, Okinawa, Japan, January 25-26 2008.

Xin Gao, Shuqian Luo, “Multi-criterion fuzzy optimization approach to imaging from incomplete projections”, Proceedings of 2005 International Conference on Fuzzy Systems and Knowledge Discovery (FSKD'05), Springer's Lecture Notes in Artificial Intelligence (LNAI) 3614, pp. 524–527, Changsha, China, August 27-29, 2005. (SCI, EI)

Xin Gao, Shuqian Luo, Zhicheng Liu, “Multi-criterion optimization algorithm for X-ray phase contrast CT imaging”, Proceedings of the 27th Annual Conference of IEEE Engineering in Medicine and Biology Society, Shanghai, China, September 1-4, 2005. (EI)

Xin Gao, Shuqian Luo, Bo Liu, Maolin Xu, et al. “An innovative microtomography algorithm of X-ray diffraction enhanced imaging”, Proceedings of International Conference on Medical Imaging and Telemedicine (MIT2005), pp. 166-171, Wuyi Palace, China, August 16-19 2005.

Hongxia Yin, Bo Liu, Xin Gao, Hang Shu, et al. “Diffraction enhanced X-ray imaging for observing guinea pig cochlea”, Proceedings of the 27th Annual Conference of IEEE Engineering in Medicine and Biology Society, Shanghai, China, September 1-4, 2005. (EI)

Hongxia Yin, Bo Liu, Xin Gao, Hang Shu, et. al. “Imaging biological micro-tissues and organs using phase-contrast X-ray imaging technique”, Proceedings of International Conference on Medical Imaging and Telemedicine (MIT2005), pp. 160-165, Wuyi Palace, China, August 16-19 2005.