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Name:
Zheng Minxue
Education:
Ph.D.
Positions:
Academic title:
Professor
Phone:
0512-69588295
Fax:
E-mail:
minxue.zheng@sibet.ac.cn
Personal Website:
Postal Code:
215163
Mailing Address:
No.88,Keling Road, Suzhou New District, China

Resume:

Direction:
Community service:

Achievements:
Article:

  Publication 

  1.       Zheng, M., Wu, M., and Tinoco, I. Jr. (2001). Formation of a GNRA tetraloop in the extended P5abc subdomain of Tetrahymena group I ribozyme can disrupt an inter-domain interaction. Proc. Natl. Acad. Sci. 98, 3695-3700. 

  2.       Kao, C., Rudisser, S. and Zheng, M. (2001). A simple and efficient method to transcribe RNAs with reduced 3' heterogeneity. Methods. 23, 201-205. 

  3.       Zheng, M., Wu, M., Silverman, S., Cech, T., and Tinoco, I., Jr. (1999). RNA folding and mutation studies of the P5abc subdomain from the tetrahymena group I intron ribozyme. FASEB Journal. 13, A1325. 

  4.       Silverman, S., Zheng, M., Wu, M., Tinoco, I. Jr. and Cech, T. R. (1999). Quantifying the energy interplay of RNA tertiary and secondary structure interactions. RNA. 5, 1665-1674. 

  5.       Kao, C., Zheng, M. and Rudisser, S. (1999). A simple and efficient method to reduce nontemplated nucleotide addition at the 3' terminus of RNAs transcribed by T7 RNA polymerase. RNA 5, 1268-1272. 

  6.       Gao, X., Huang, X., Zheng, M., Smith, G. K., and Ji, J. (1998). Structure, flexibility and folding of single stranded DNA triplet repeats. Biophysical Journal. 74, A333. 

  7.       Zheng, M., Huang, X., Smith, K., Yang, X. and Gao, X. (1996). Genetically unstable CXG repeats are structurally dynamic and have a high propensity for folding. An NMR and UV spectroscopic study. J. Mol. Biol. 264, 323–336. 

  8.       Gao, X., Huang, X., Smith, G. K., Zheng, M., and Liu. H. (1995). A new antiparallel duplex Motif of DNA CCG repeats that is stabilized by extrahelical bases symmetrically located in the minor groove. J. Am. Chem. Soc. 117, 8883-8884. 

  9.       Gao, X., Smith, K., Huang, X., and Zheng, M. (1995). Unusual solution structures unveiled by NMR studies of single-stranded DNA triplet repeats. FASEB Journal. 9, A1324. 

  10.   Gao, X., Smith, K., Huang, X., Zheng, M., and Liu, H. (1995). Journal of Cellular Biochemistry Supplement. 0, 58. 

  11.   Wang, W., Liang, C., Zheng, M., and Gao, X. (1995). Selective acylation of N-(2-Phosphonoethyl) ethylenediamine phosphonates. Tetrahedron Letters 36, 1181-1184. 

  12.   Zheng, M. and Tinoco, I. Jr. (2000). High resolution NMR spectroscopy of ribozymes. In Ribozyme Biochemistry and Biotechnology. 297-314, Eds. Krupp. G. and Gaur, R. Eaton Publishing, Natick. [Invited book chapter]. 

  13.   Gao, X., Huang, X., Smith, G. K., Zheng, M. (1998). Structure and dynamics of single stranded nucleic acids containing trinucleotide repeats. In Genetic instabilities and hereditary neurological diseases, 623-644. Eds. Warren, S. T. and Wells, R. D., Academic Press, San Diego. [Invited review].  

  Patent 

  1.       Zheng, M., Quinn, J., and Warner, B. (2013). Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation. Patent No. US 8394944 B2, issue date 3/12/2013. 

  2.       Zheng, M., Ku, L. Shen, L. Wong, C. and Bush-Donovan, C. (2013). Reagents and methods for detecting CYP2C9 polymorphisms, Patent No. EP2111465B1, issue date 12/04/2013. 

  3.       Battersby, T., Fehr, A. and Zheng, M. (2013).A method of normalizing biological samples. Patent No. WO 2014015098 A1, issue date 3/18/2013. 

  4.       Fehr, A., Battersby, T. and Zheng, M. (2012). Dynamic Range Compression of Nucleic Acid Library Input for Next Generation Sequencing Systems. US provisional patent number 2012P10835US. 

  5.       Zheng, M., Ahle, D., Warner, B., Wu, M. and Chang, C. (2011). Highly orthogonal universal sequences for use in nucleic acid assays. Patent No: US8063196B2, issue date 11/22/2011. 

  6.       Schwers, S. and Zheng, M. (2010). E7-Gene-Specific Primers and Probes to Detect Human Papillomavirus (HPV) in Cervical Cancer Screening. Siemens memorandum of invention (MOI) filed for patent application in Germany, Brief-ID: 3299360. 

  7.     Quinn, J., Zheng, M., and Warner, B. (2004). Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation. Patent No:EP1428892A1. Patent issued in EU (2007).

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