The main research direction is the development of in vitro diagnostic reagents related to blood transfusion safety. Member of the Expert Committee of Liquid Biopsy Technology of the Second China Association of Integrative Medicine, Laboratory Medicine Professional Committee.

Committed to the research of molecular and immune POCT detection technology, as the project leader, he applied for the approval of Jiangsu Youth Fund, Jiangsu Postdoctoral Fund, and enterprise horizontal projects.

As the first author or corresponding author has published 8 papers, 4 authorized invention patents, 7 utility model patents, and 2 appearance patents.

Focusing on blood immunology, on the one hand, it combines classical detection technology with sound, light, magnetic, and electrical technologies to develop new type of immunodiagnostic technology; on the other hand, it combines unique nucleic acid extraction technology with body temperature amplification technology to develop Molecular diagnostic techniques for families and communities.

(1) Molecular diagnostic technology based on RPA amplification technology: using isothermal amplification technology, gene editing enzymes and restriction enzymes, etc., to carry out research on the detection of infectious microorganisms, and to provide fast and accurate solutions for clinical practice.

(2) Research on enzymatic chemiluminescence POCT detection technology: research on new POCT chemiluminescence technology.

1. Mur (MNS 10) screening with a novel loop-mediated isothermal amplification assay in Zhongshan, China. Transfusion Medicine, 2016.6, 26(3): 215~219

2. Chicken Egg Yolk Antibodies (IgYs) block the binding of Multiple SARS-CoV-2 Spike protein variants to human ACE2. Int Immunopharmacol. 2021 Jan;90:107172. doi: 10.1016/j.intimp.2020.107172

3. Intein-Mediated Protein trans-Splicing of the Recombinant Streptavidin on Magnetosomes. Mol Biol. Nov-Dec 2021;55(6):982-986. doi: 10.31857/S0026898421060057.

4. Natural Silk cocoon membrane-based versatile and stable immunosensing platform. Sensors and Actuators B: Chemical.2020-05-30 , DOI: 10.1016/j.snb.2020.128376

5. Research and application of inactive human cell-dependent blood group antigens[J]. Chinese Journal of Immunology, 2015, 31(2):4.

6. Identification and application of human Mur blood group antibodies: a case report [J]. China Journal of Blood Transfusion, 2016, 29(12):4.

7. Advances in the application of nucleic acid diagnostic technology of CRISPR/Cas system [J]. Journal of Molecular Diagnosis and Therapy, 2021, 13(11):5.

8. Inhibitory effect of AAV-mediated RNAi on SARS-CoV-2 S gene expression[J]. Biotechnology Bulletin, 2021

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